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1

HMGB1 and LPS induce distinct patterns of gene expression and activation in neutrophils from patients with sepsis-induced acute lung injury

Eliezer Silva, John Arcaroli, Qianbin He, Daiva Svetkauskaite, Christopher Coldren, Jerry A. Nick, Katie Poch, Jong Sung Park, Anirban Banerjee, Edward Abraham

Journal:

Intensive Care Medicine

Année:

2007

Langue:

english

Fichier:

PDF, 173 KB

english, 2007

2

Association between urokinase haplotypes and outcome from infection-associated acute lung injury

John Arcaroli, Jeff Sankoff, Nianjun Liu, David B. Allison, James Maloney, Edward Abraham

Journal:

Intensive Care Medicine

Année:

2008

Langue:

english

Fichier:

PDF, 120 KB

english, 2008

3

Is a Duplication of 14q32 a New Recurrent Chromosomal Alteration in B-Cell Non-Hodgkin Lymphoma?

John J Arcaroli, Bhavana J Dave, Diane L Pickering, Michelle M Hess, James O Armitage, Dennis D Weisenburger, Warren G Sanger

Journal:

Cancer Genetics and Cytogenetics

Année:

1999

Langue:

english

Fichier:

PDF, 269 KB

english, 1999

4

Involvement of phosphatidylinositol 3-kinase γ in neutrophil apoptosis

Kuang-Yao Yang, John Arcaroli, John Kupfner, Todd M Pitts, Jong Sung Park, Derek Strasshiem, Reury-Perng Perng, Edward Abraham

Journal:

Cellular Signalling

Année:

2003

Langue:

english

Fichier:

PDF, 322 KB

english, 2003

5

Similarity-Based Multimarker Association Tests for Continuous Traits

Wan-Yu Lin, Hemant K. Tiwari, Guimin Gao, Kui Zhang, John J. Arcaroli, Edward Abraham, Nianjun Liu

Journal:

Annals of Human Genetics

Année:

2012

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2012

6

Biomarker-driven trial in metastatic pancreas cancer: feasibility in a multicenter study of saracatinib, an oral Src inhibitor, in previously treated pancreatic cancer

John Arcaroli, Kevin Quackenbush, Arvind Dasari, Rebecca Powell, Martine McManus, Aik-Choon Tan, Nathan R. Foster, Joel Picus, John Wright, Sujatha Nallapareddy, Charles Erlichman, Manuel Hidalgo, Wel

Journal:

Cancer Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2012

7

Role of p38 MAP Kinase in the Development of Acute Lung Injury

John Arcaroli, Ho-Kee Yum, John Kupfner, Jong Sung Park, Kuang-Yao Yang, Edward Abraham

Journal:

Clinical Immunology

Année:

2001

Langue:

english

Fichier:

PDF, 125 KB

english, 2001

8

ALDH+ tumor-initiating cells exhibiting gain in NOTCH1 gene copy number have enhanced regrowth sensitivity to a γ-secretase inhibitor and irinotecan in colorectal cancer

John J. Arcaroli, Rebecca W. Powell, Marileila Varella-Garcia, Martine McManus, Aik Choon Tan, Kevin S. Quackenbush, Todd M. Pitts, Dexiang Gao, Anna Spreafico, Arvind Dasari, Basel M. Touban, Wells A

Journal:

Molecular Oncology

Année:

2012

Langue:

english

Fichier:

PDF, 2.14 MB

english, 2012

9

Patient-derived tumour xenografts as models for oncology drug development

Tentler, John J., Tan, Aik Choon, Weekes, Colin D., Jimeno, Antonio, Leong, Stephen, Pitts, Todd M., Arcaroli, John J., Messersmith, Wells A., Eckhardt, S. Gail

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Année:

2012

Langue:

english

Fichier:

PDF, 4.64 MB

english, 2012

10

THE NEGLECTED CHILD IN HIS OWN HOME

Tan, A., Britt, B., Astling, D., Leong, S., Lieu, C., Tentler, J., Pitts, T., Arcaroli, J., Messersmith, W., Eckhardt, S.

Journal:

Année:

1948

Langue:

english

Fichier:

PDF, 402 KB

english, 1948

11

263 Validation of Preclinical Colorectal Cancer Models Against TCGA Data for Pathway Analysis and Predictive Biomarker Discovery

Tan, A., Britt, B., Astling, D., Leong, S., Lieu, C., Tentler, J., Pitts, T., Arcaroli, J., Messersmith, W., Eckhardt, S.

Journal:

European Journal of Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 55 KB

english, 2012

12

Stromal Cell-Derived Factor 1α Mediates Resistance to mTOR-Directed Therapy in Pancreatic Cancer

Weekes, Colin D., Song, Dongweon, Arcaroli, John, Wilson, Lora A., Rubio-Viqueira, Belen, Cusatis, George, Garrett-Mayer, Elizabeth, Messersmith, Wells A., Winn, Robert A., Hidalgo, Manuel

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.94 MB

english, 2012

13

485 Targeting the MAP Kinase and Wnt Signaling Pathways in Preclinical Models of Colorectal Cancer

Spreafico, A., Klauck, P.J., Tentler, J.J., Pitts, T.M., Tan, A.C., Kim, J., Gregory, M.A., McManus, M.C., Arcaroli, J.J.

Journal:

European Journal of Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 60 KB

english, 2012

14

A phase II study of the gamma secretase inhibitor RO4929097 in patients with previously treated metastatic pancreatic adenocarcinoma

De Jesus-Acosta, Ana, Laheru, Daniel, Maitra, Anirban, Arcaroli, John, Rudek, Michelle A., Dasari, Arvind, Blatchford, Patrick J., Quackenbush, Kevin, Messersmith, Wells

Journal:

Investigational New Drugs

Année:

2014

Langue:

english

Fichier:

PDF, 199 KB

english, 2014

15

Activation of gene expression in human neutrophils by high mobility group box 1 protein

Park, J. S., Arcaroli, J., Yum, H.-K., Yang, H., Wang, H., Yang, K.-Y., Choe, K.-H., Strassheim, D., Pitts, T. M., Tracey, K. J., Abraham, E.

Journal:

AJP Cell Physiology

Année:

2003

Langue:

english

Fichier:

PDF, 353 KB

english, 2003

16

Phase I pharmacokinetic and pharmacodynamic study of cetuximab, irinotecan and sorafenib in advanced colorectal cancer

Nilofer Azad,Arvind Dasari,John Arcaroli,Gretchen E. Taylor…

Journal:

Investigational New Drugs

Année:

2013

Langue:

english

Fichier:

PDF, 240 KB

english, 2013

17

Gene expression and intracellular NF-κB activation after HMGB1 and LPS stimuli in neutrophils from septic patients

E Silva,J Arcaroli,Q He,D Svetkauskaite,C Coldren,J Nick,K Poch…

Journal:

Critical Care (BioMed Central)

Année:

2005

Langue:

english

Fichier:

PDF, 567 KB

english, 2005

18

Decreased activation of NF-κB and expression of related genes in IRAK-1SNP 532neutrophils from volunteers exposed to endotoxin and in unstimulated neutrophils from septic patients

J Arcaroli,E Silva,Q He,D Svetkauskaite,C Coldren,J Maloney,JS Park…

Journal:

Critical Care (BioMed Central)

Année:

2005

Langue:

english

Fichier:

PDF, 567 KB

english, 2005

19

Association between IL-32 genotypes and outcome in infection-associated acute lung injury

John J Arcaroli,Nianjun Liu,Nengjun Yi,Edward Abraham

Journal:

Critical Care (BioMed Central)

Année:

2011

Langue:

english

Fichier:

PDF, 547 KB

english, 2011

20

Cutting Edge: HMG-1 as a Mediator of Acute Lung Inflammation

Abraham, E., Arcaroli, J., Carmody, A., Wang, H., Tracey, K. J.

Journal:

The Journal of Immunology

Année:

2000

Langue:

english

Fichier:

PDF, 650 KB

english, 2000

21

Tumours with elevated levels of the Notch and Wnt pathways exhibit efficacy to PF-03084014, a γ-secretase inhibitor, in a preclinical colorectal explant model

Arcaroli, J J, Quackenbush, K S, Purkey, A, Powell, R W, Pitts, T M, Bagby, S, Tan, A C, Cross, B, McPhillips, K, Song, E-K, Tai, W M, Winn, R A, Bikkavilli, K, VanScoyk, M, Eckhardt, S G, Messersmith

Journal:

British Journal of Cancer

Année:

2013

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2013

22

Wnt7a is a novel inducer of β-catenin-independent tumor-suppressive cellular senescence in lung cancer

Bikkavilli, R K, Avasarala, S, Van Scoyk, M, Arcaroli, J, Brzezinski, C, Zhang, W, Edwards, M G, Rathinam, M K K, Zhou, T, Tauler, J, Borowicz, S, Lussier, Y A, Parr, B A, Cool, C D, Winn, R A

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 5.21 MB

english, 2015

23

Role of NF- B in Endotoxemia-Induced Alterations of Lung Neutrophil Apoptosis

Kupfner, J. G., Arcaroli, J. J., Yum, H.-K., Nadler, S. G., Yang, K.-Y., Abraham, E.

Journal:

The Journal of Immunology

Année:

2001

Langue:

english

Fichier:

PDF, 374 KB

english, 2001

24

Preclinical Activity of the Rational Combination of Selumetinib (AZD6244) in Combination with Vorinostat in KRAS-Mutant Colorectal Cancer Models

Morelli, M. P., Tentler, J. J., Kulikowski, G. N., Tan, A.-C., Bradshaw-Pierce, E. L., Pitts, T. M., Brown, A. M., Nallapareddy, S., Arcaroli, J. J., Serkova, N. J., Hidalgo, M., Ciardiello, F., Eckha

Journal:

Clinical Cancer Research

Année:

2012

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2012

25

Involvement of Phosphoinositide 3-Kinases in Neutrophil Activation and the Development of Acute Lung Injury

Yum, H.-K., Arcaroli, J., Kupfner, J., Shenkar, R., Penninger, J. M., Sasaki, T., Yang, K.-Y., Park, J. S., Abraham, E.

Journal:

The Journal of Immunology

Année:

2001

Langue:

english

Fichier:

PDF, 417 KB

english, 2001

26

Gene Array and Fluorescence In situ Hybridization Biomarkers of Activity of Saracatinib (AZD0530), a Src Inhibitor, in a Preclinical Model of Colorectal Cancer

Arcaroli, J. J., Touban, B. M., Tan, A. C., Varella-Garcia, M., Powell, R. W., Eckhardt, S. G., Elvin, P., Gao, D., Messersmith, W. A.

Journal:

Clinical Cancer Research

Année:

2010

Langue:

english

Fichier:

PDF, 622 KB

english, 2010

27

Identification of Predictive Markers of Response to the MEK1/2 Inhibitor Selumetinib (AZD6244) in K-ras-Mutated Colorectal Cancer

Tentler, J. J., Nallapareddy, S., Tan, A. C., Spreafico, A., Pitts, T. M., Morelli, M. P., Selby, H. M., Kachaeva, M. I., Flanigan, S. A., Kulikowski, G. N., Leong, S., Arcaroli, J. J., Messersmith, W

Journal:

Molecular Cancer Therapeutics

Année:

2010

Langue:

english

Fichier:

PDF, 791 KB

english, 2010

28

Common PIK3CA Mutants and a Novel 3' UTR Mutation Are Associated with Increased Sensitivity to Saracatinib

Arcaroli, J. J., Quackenbush, K. S., Powell, R. W., Pitts, T. M., Spreafico, A., Varella-Garcia, M., Bemis, L., Tan, A. C., Reinemann, J. M., Touban, B. M., Dasari, A., Eckhardt, S. G., Messersmith, W

Journal:

Clinical Cancer Research

Année:

2012

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2012

29

Urokinase-Type Plasminogen Activator Potentiates Lipopolysaccharide-Induced Neutrophil Activation

Abraham, E., Gyetko, M. R., Kuhn, K., Arcaroli, J., Strassheim, D., Park, J. S., Shetty, S., Idell, S.

Journal:

The Journal of Immunology

Année:

2003

Langue:

english

Fichier:

PDF, 394 KB

english, 2003

30

Bilateral Cochlear Implants in Adults and Children

Litovsky, Ruth Y., Parkinson, Aaron, Arcaroli, Jennifer, Peters, Robert, Lake, Jennifer, Johnstone, Patti, Yu, Gonqiang

Journal:

Archives of Otolaryngology - Head and Neck Surgery

Année:

2004

Langue:

english

Fichier:

PDF, 142 KB

english, 2004

31

Extracellular Superoxide Dismutase Haplotypes Are Associated with Acute Lung Injury and Mortality

Arcaroli, John J., Hokanson, John E., Abraham, Edward, Geraci, Mark, Murphy, James R., Bowler, Russell P., Dinarello, Charles A., Silveira, Lori, Sankoff, Jeff, Heyland, Daren, Wischmeyer, Paul, Crapo

Journal:

American Journal of Respiratory and Critical Care Medicine

Année:

2009

Langue:

english

Fichier:

PDF, 503 KB

english, 2009

32

Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/Calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer

Spreafico, A., Tentler, J. J., Pitts, T. M., Tan, A. C., Gregory, M. A., Arcaroli, J. J., Klauck, P. J., McManus, M. C., Hansen, R. J., Kim, J., Micel, L. N., Selby, H. M., Newton, T. P., McPhillips,

Journal:

Clinical Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2013

33

Variant IRAK-1 Haplotype Is Associated with Increased Nuclear Factor–κB Activation and Worse Outcomes in Sepsis

Arcaroli, John, Silva, Eliezer, Maloney, James P., He, Qianbin, Svetkauskaite, Daiva, Murphy, James R., Abraham, Edward

Journal:

American Journal of Respiratory and Critical Care Medicine

Année:

2006

Fichier:

PDF, 158 KB

2006

34

Extracellular Superoxide Dismutase Attenuates Lung Injury after Hemorrhage

BOWLER, RUSSELL P., ARCAROLI, JOHN, CRAPO, JAMES D., ROSS, ARON, SLOT, JAN W., ABRAHAM, EDWARD

Journal:

American Journal of Respiratory and Critical Care Medicine

Année:

2001

Langue:

english

Fichier:

PDF, 105 KB

english, 2001

35

Variant IRAK-1 Haplotype Is Associated with Increased Nuclear Factor–κB Activation and Worse Outcomes in Sepsis

Arcaroli, John, Silva, Eliezer, Maloney, James P., He, Qianbin, Svetkauskaite, Daiva, Murphy, James R., Abraham, Edward

Journal:

American Journal of Respiratory and Critical Care Medicine

Année:

2006

Langue:

english

Fichier:

PDF, 158 KB

english, 2006

36

Targeting the WNT Signaling Pathway in Cancer Therapeutics

Tai, D., Wells, K., Arcaroli, J., Vanderbilt, C., Aisner, D. L., Messersmith, W. A., Lieu, C. H.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 872 KB

english, 2015

37

Early Alterations in Neutrophil Activation Are Associated with Outcome in Acute Lung Injury

Yang, Kuang-Yao, Arcaroli, John J., Abraham, Edward

Journal:

American Journal of Respiratory and Critical Care Medicine

Année:

2003

Langue:

english

Fichier:

PDF, 186 KB

english, 2003

38

hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression

Avasarala, S., Van Scoyk, M., Wang, J., Sechler, M., Vandervest, K., Brzezinski, C., Weekes, C., Edwards, M. G., Arcaroli, J., Davis, R. E., Bikkavilli, R. K., Winn, R. A.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 912 KB

english, 2013

39

Topoisomerase IIα mediates TCF-dependent epithelial–mesenchymal transition in colon cancer

Zhou, Q, Abraham, A D, Li, L, Babalmorad, A, Bagby, S, Arcaroli, J J, Hansen, R J, Valeriote, F A, Gustafson, D L, Schaack, J, Messersmith, W A, LaBarbera, D V

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 2.81 MB

english, 2016

40

GENETIC POLYMORPHISMS AND SEPSIS

Arcaroli, John, Fessler, Michael B, Abraham, Edward

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 231 KB

english, 2005

41

Wnt7a is a novel inducer of β-catenin-independent tumor-suppressive cellular senescence in lung cancer

Bikkavilli, R K, Avasarala, S, Van Scoyk, M, Arcaroli, J, Brzezinski, C, Zhang, W, Edwards, M G, Rathinam, M K K, Zhou, T, Tauler, J, Borowicz, S, Lussier, Y A, Parr, B A, Cool, C D, Winn, R A

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 61 KB

english, 2015

42

Multichannel auditory brainstem implant: US clinical trial results

Ebinger, K., Otto, S., Arcaroli, J., Staller, S., Arndt, P.

Journal:

Journal of Laryngology & Otology

Année:

2000

Langue:

english

Fichier:

PDF, 280 KB

english, 2000

43

The Nucleus?? 24 Contour??? Cochlear Implant System: Adult Clinical Trial Results

Parkinson, Aaron J., Arcaroli, Jennifer, Staller, Steven J., Arndt, Patti L., Cosgriff, Anne, Ebinger, Kiara

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2002

44

617 CDK1 promotes tumor initiation by interacting with Sox2 and enhancing its function

Luo, Y., Arcaroli, J.J., Liu, S., Kutty, L.K., Bagby, S., Messersmith, W., Fujita, M.

Journal:

The Journal of Investigative Dermatology

Année:

2016

Langue:

english

Fichier:

PDF, 52 KB

english, 2016

45

Evaluation of Equivalency in Two Recordings of Monosyllabic Words

Skinner, Margaret W., Holden, Laura K., Fourakis, Marios S., Hawks, John W., Holden, Timothy, Arcaroli, Jennifer, Hyde, Martyn

Journal:

Journal of the American Academy of Audiology

Année:

2006

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2006

46

Activation of Extracellular Signal-Regulated Kinases, NF- B, and Cyclic Adenosine 5'-Monophosphate Response Element-Binding Protein in Lung Neutrophils Occurs by Differing Mechanisms After Hemorrhage or Endotoxemia

Abraham, E., Arcaroli, J., Shenkar, R.

Journal:

The Journal of Immunology

Année:

2001

Langue:

english

Fichier:

PDF, 753 KB

english, 2001

47

Simultaneous Bilateral Cochlear Implantation in Adults: A Multicenter Clinical Study

Litovsky, Ruth, Parkinson, Aaron, Arcaroli, Jennifer, Sammeth, Carol

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2006

48

Spatial Hearing and Speech Intelligibility in Bilateral Cochlear Implant Users

Litovsky, Ruth Y., Parkinson, Aaron, Arcaroli, Jennifer

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2009

49

Clinical Evaluation of Higher Stimulation Rates in the Nucleus Research Platform 8 System

Plant, Kerrie, Holden, Laura, Skinner, Margo, Arcaroli, Jennifer, Whitford, Lesley, Law, Mary-Ann, Nel, Esti

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 825 KB

english, 2007

50

Aldehyde Dehydrogenase 1B1 as a Modulator of Pancreatic Adenocarcinoma

Singh, Surendra, Arcaroli, John J., Orlicky, David J., Chen, Ying, Messersmith, Wells A., Bagby, Stacey, Purkey, Alicia, Quackenbush, Kevin S., Thompson, David C., Vasiliou, Vasilis

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 357 KB

english, 2016